Drug interactions with bosentan oral and abiraterone oral

bosentan oral brand names and other generic formulations include:

Tracleer Oral

All generic drug interactions for bosentan oral (lists will include brand and generic names):

abiraterone oral brand names and other generic formulations include:

Zytiga Oral

All generic drug interactions for abiraterone oral (lists will include brand and generic names):
Monitor CloselyPotential for significant interaction (monitoring by your doctor is likely required)

bosentan oral and abiraterone oral

bosentan oral decreases levels of abiraterone oral by altering drug metabolism. Avoid taking this combination together; if it cannot be avoided, your doctor may increase abiraterone dosage frequency from once a day to twice a day.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyModify Therapy/Monitor Closely.

bosentan oral and abiraterone oral

bosentan oral decreases levels of abiraterone oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid coadministration of abiraterone with strong CYP3A4 inducers; if a strong CYP3A4 inducer must be used, increase abiraterone dosage frequency from once daily to twice daily

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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