Drug interactions with bosentan oral and amlodipine oral

bosentan oral brand names and other generic formulations include:

Tracleer Oral

All generic drug interactions for bosentan oral (lists will include brand and generic names):

amlodipine oral brand names and other generic formulations include:

Norvasc Oral

All generic drug interactions for amlodipine oral (lists will include brand and generic names):
Monitor CloselySignificant interaction possible (monitoring by your doctor required)

bosentan oral and amlodipine oral

bosentan oral will decrease the level or effect of amlodipine oral by altering drug metabolism.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyUse Caution/Monitor.

bosentan oral and amlodipine oral

bosentan oral will decrease the level or effect of amlodipine oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor for decreased effects of amlodipine (CYP3A4 substrate) if bosentan is initiated/dose increased. Also, monitor toxicities of amlodipine if bosentan is discontinued/dose decreased.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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