
bosentan oral brand names and other generic formulations include:
axitinib oral brand names and other generic formulations include:
bosentan oral and axitinib oral
bosentan oral decreases levels of axitinib oral by altering drug metabolism. One drug reduces levels of the other. This combination should be avoided if possible.
bosentan oral and axitinib oral
bosentan oral decreases levels of axitinib oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Selection of concomitant medication with no or minimal CYP3A4 induction potential is recommended
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant