bosentan oral brand names and other generic formulations include:
cpm-pseudoephed-hydrocodone oral brand names and other generic formulations include:
A-G Tussin Oral, Amtussin Oral, C-Cof HC Oral, Coldcough HC Oral, Coldtuss Oral, Cordron-HC Oral, Genecof-HC Oral, Histinex PV Oral, Hycofed Oral, HYDROCOF-HC Oral, Hydron PSC Oral, Hydro-Tussin HC Oral, Hyphed Oral, Jaycof-HC Oral, KG-Tussin Oral, MedTussin Oral, M-End (with Chlorpheniramine) Oral, Notuss Oral, Notuss-Forte Oral, Pediatex HC Oral, Tussin-V Oral, Tuss-PV Oral, WellTuss HC Oral, Zutripro Oral
bosentan oral and cpm-pseudoephed-hydrocodone oral
bosentan oral will decrease the level or effect of cpm-pseudoephed-hydrocodone oral by altering drug metabolism. Blood levels of hydrocodone may be reduced but may increase upon stopping the interacting drug which can result in potentially life-threatening respiratory depression (difficulty breathing).
bosentan oral and cpm-pseudoephed-hydrocodone oral
bosentan oral will decrease the level or effect of cpm-pseudoephed-hydrocodone oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Caution when discontinuing CYP3A4 inducers that are coadministered with hydrocodone; plasma concentrations of hydrocodone may increase and can result in potentially fatal respiratory depression
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant