Drug interactions with bosentan oral and saquinavir base oral

bosentan oral brand names and other generic formulations include:

Tracleer Oral

All generic drug interactions for bosentan oral (lists will include brand and generic names):

saquinavir base oral brand names and other generic formulations include:

Fortovase Oral

All generic drug interactions for saquinavir base oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

bosentan oral and saquinavir base oral

bosentan oral will decrease the level or effect of saquinavir base oral by altering drug metabolism. Under the care of your doctor, stop taking bosentan more than 36 hours prior to starting the protease inhibitor and restart 10 days after the starting of the protease inhibitor, at 62.5 mg once daily or every other day.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Serious - Use AlternativeAvoid or Use Alternate Drug.

bosentan oral and saquinavir base oral

bosentan oral will decrease the level or effect of saquinavir base oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. stop bosentan >36 hours prior to PI initiation and restart 10 days after PI initiation at 62.5 mg once daily or every other day.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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