Drug interactions with bupropion hbr oral and pimozide oral

bupropion hbr oral brand names and other generic formulations include:

Aplenzin Oral

All generic drug interactions for bupropion hbr oral (lists will include brand and generic names):

pimozide oral brand names and other generic formulations include:

Orap Oral

All generic drug interactions for pimozide oral (lists will include brand and generic names):
ContraindicatedNever use this combination of drugs because of high risk for dangerous interaction

bupropion hbr oral and pimozide oral

bupropion hbr oral will increase the level or effect of pimozide oral by altering drug metabolism. Combination may increase risk of seizures and reduce breakdown of both drug.

Patient Drug Interactions Source: RxList
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ContraindicatedContraindicated.

bupropion hbr oral and pimozide oral

bupropion hbr oral will increase the level or effect of pimozide oral by affecting hepatic enzyme CYP2D6 metabolism. Both bupropion and hydroxybupropion (major metabolite) are considered strong CYP2D6 inhibitors; additionally, bupropion and pimozide lower seizure threshold

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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