
bupropion hcl oral brand names and other generic formulations include:
Budeprion SR Oral, Budeprion XL Oral, Buproban Oral, Forfivo XL Oral, Wellbutrin Oral, Wellbutrin SR Oral, Wellbutrin XL Oral, Zyban Oral
eliglustat oral brand names and other generic formulations include:
Cerdelga Oral
bupropion hcl oral and eliglustat oral
bupropion hcl oral increases levels of eliglustat oral by altering drug metabolism. Your doctor will reduce the dose of eliglustat when it is given with drugs that can moderately reduce its breakdown. Do not combine with drugs that significantly reduce the breakdown of eliglustat.
bupropion hcl oral and eliglustat oral
bupropion hcl oral increases levels of eliglustat oral by affecting hepatic enzyme CYP2D6 metabolism. If coadministered with strong or moderate CYP2D6 inhibitors, reduce eliglustat dose from 84 mg BID to 84 mg once daily in extensive and intermediate metabolizers; eliglustat is contraindiated if strong or moderate CYP2D6 inhibitors are given concomitantly with strong or moderate CYP3A inhibitors
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant