
bupropion hcl oral brand names and other generic formulations include:
Budeprion SR Oral, Budeprion XL Oral, Buproban Oral, Forfivo XL Oral, Wellbutrin Oral, Wellbutrin SR Oral, Wellbutrin XL Oral, Zyban Oral
pimozide oral brand names and other generic formulations include:
bupropion hcl oral and pimozide oral
bupropion hcl oral will increase the level or effect of pimozide oral by altering drug metabolism. Combination may increase risk of seizures and reduce breakdown of both drug.
bupropion hcl oral and pimozide oral
bupropion hcl oral will increase the level or effect of pimozide oral by affecting hepatic enzyme CYP2D6 metabolism. Both bupropion and hydroxybupropion (major metabolite) are considered strong CYP2D6 inhibitors; additionally, bupropion and pimozide lower seizure threshold
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant