
candesartan-hydrochlorothiazide oral brand names and other generic formulations include:
aliskiren-amlodipine oral brand names and other generic formulations include:
candesartan-hydrochlorothiazide oral and aliskiren-amlodipine oral
candesartan-hydrochlorothiazide oral decreases effects of aliskiren-amlodipine oral by Other mechanism.
candesartan-hydrochlorothiazide oral and aliskiren-amlodipine oral
candesartan-hydrochlorothiazide oral decreases effects of aliskiren-amlodipine oral by Other (see comment). Aliskiren use contraindicated with ARBs in patients with diabetes; avoid coadministration with ARBs if GFR. In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of ARBS with drugs that affect RAAS may increase the risk of renal impairment (including acute renal failure) and cause loss of antihypertensive effect. Monitor renal function periodically.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant