
carbamazepine oral brand names and other generic formulations include:
Atretol Oral, Carbatrol Oral, Epitol Oral, Equetro Oral, Tegretol Oral, Tegretol XR Oral
ibrutinib oral brand names and other generic formulations include:
Imbruvica Oral
carbamazepine oral and ibrutinib oral
carbamazepine oral decreases levels of ibrutinib oral by altering drug metabolism. Ibrutinib blood concentrations may decrease by ~10-fold.
carbamazepine oral and ibrutinib oral
carbamazepine oral decreases levels of ibrutinib oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Strong CYP3A inducers decrease ibrutinib plasma concentrations by ~10-fold
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant