Drug interactions with chlorpheniramine-pseudoeph-dextromethorph-acetaminophen oral and diphenhydramine oral

chlorpheniramine-pseudoeph-dextromethorph-acetaminophen oral brand names and other generic formulations include:

666 Cough & Cold Oral, Acute Cold Formula Oral, Alka-Seltzer Plus Cold/Cough (PSE) Oral, Alka-Seltzer Plus-D Sinus-Cold Oral, Apdc Cold Oral, Bayer Select Flu Relief Oral, Child Cold Oral, Child Non-Aspirin Cough & Cold Oral, Child Pain Relief Cold-Cough Oral, Children's Cold Plus Cough Oral, Children's Flu Oral, Children's Mapap Cold/Cough Oral, Children's Multi-Symptom Plus Oral, Children's Non-Aspirin Plus Oral, Children's Tylenol Cold-Cough Oral, Children's Tylenol Flu Oral, Co-APAP Oral, Cold & Cough Relief Oral, Cold Care Oral, Cold Formula-M Oral, Cold Relief W/o Aspirin Oral, Cold Relief Without Aspirin Oral, Cold Reliever Maximum Strength Oral, Cold Symptom Relief Oral, Cold/Flu/Sinus Relief Oral, Cold-Flu-Cough Oral, Combination Cold Oral, Combination Symptom Cold Oral, Complete Cold And Flu Oral, Complete Cold Medicine Oral, Complete Cold Oral, Complete Symptom Cold Relief Oral, Comtrex Day & Night Oral, Comtrex Multi-Symptom Cold/Flu Oral, Comtrex Multi-Symptom Oral, CoTylenol Oral, Cough & Cold Plus Oral, Cough & Cold Tab Oral, Cough FM Decong Oral, Cough Syrup M Oral, Cough, Cold & Flu Relief-M Oral, Cough/Cold Childs APAP Oral, Cough-Cold & Flu Relief Oral, Decongestant Ad X-Str Oral, Deconol Oral, Dristan Ultra Cold Formula Oral, Ex-Prin Cold And Cough Oral, Ex-Prin Mult-Sym Child Cold Oral, Flu & Cold Medicine (DM) Oral, Flu, Cold & Cough Medicine Oral, Flu, Cough & Cold Medicine Oral, Flu/Cough/Cold Oral, Flu-Cold-Cough Night Time Oral, Flu-Cold-Cough Nighttime Oral, Flu-Cough-Cold Max Strength Oral, Flu-Cough-Cold Oral, Formula M Cough,Cold & Flu Oral, Genacol Max St Cold/Flu Relief Oral, Genapap-C Oral, Intense Cold Remedy Oral, Kolephrin-DM Oral, Max Strength Complete Oral, Medi-Flu Oral, Multi Symptom Child Cold/Cough Oral, Multi Symptom Cold Oral, Multi Symptom Cough/Cold Form Oral, Multidexol M Oral, Multi-Symptom Cold Oral, Multi-Symptom Cold Relief Oral, Multi-Symptom Cold Reliever Oral, Multi-Symptom Cold/Flu Relief Oral, NightTime Cold-Cough Oral, Nighttime Flu,Cold & Cough Oral, Nighttime Flu-Cold-Cough Oral, Non Aspirin Cold Complete Form Oral, Non Aspirin Cold Plus Cough Oral, Non-Aspirin Cold Formula Oral, Non-Aspirin Cold Plus Cough Oral, Non-Aspirin Plus Cold & Cough Oral, Pain Relief Plus Flu Oral, Pain Reliever Flu Child Oral, Severe Cold/Flu Maximum Str Oral, St. Joseph Night Cold Relief Oral, Symptomatic Cold Relief Oral, Symptomatic Cold Tablet Oral, T.P.I. Oral, Theraflu MS Severe Cold &Cough Oral, Theraflu Nighttime Formula Oral, Theraflu Severe Cold-Cough Oral, Ty-Cold Formula Oral, Tylenol Cold Oral, Ultra Flu Oral, Ultrex Oral, Uni-Coace Oral, Vicks Formula 44M Oral

All generic drug interactions for chlorpheniramine-pseudoeph-dextromethorph-acetaminophen oral (lists will include brand and generic names):

diphenhydramine oral brand names and other generic formulations include:

40 Winks Oral, Acadryl Oral, Adult Allergy Oral, Aid To Sleep Oral, Aledryl Oral, Aler-Cap Oral, Aler-Dryl Oral, Aler-Tab Oral, Alka-Seltzer Plus Allergy Oral, Alledryl Oral, Aller Med Oral, Allergia-C Oral, Aller-G-Time Oral, Allergy (diphenhydramine) Oral, Allergy Capsule Oral, Allergy Elixir Oral, Allergy Medication Oral, Allergy Medicine Complete Oral, Allergy Medicine Oral, Allergy Oral, Allergy Relief (diphenhydramine) Oral, Altaryl Oral, Antihist Oral, Antihistamine Allergy Oral, Anti-Hyst Oral, Antitussive Cough Oral, Banophen Allergy Oral, Banophen Oral, Baramine Oral, Beldin Oral, Belix Oral, Benadryl Allergy Oral, Benadryl Allergy Quick Dissolve Oral, Benadryl Dye-Free Allergy Oral, Benadryl Fastmelt Oral, Benadryl Oral, Benaphen Oral, Bendramine Oral, Bendramine-25 Oral, Bendramine-50 Oral, Bendylate Oral, Ben-Rex Oral, Bentrac 25 Oral, Bentrac 50 Oral, Bentrac Oral, Bet-R-Rest Oral, Bydramine Oral, Calhistryl Oral, Calm-Aid Oral, Children's Allergy (diphenhydramine) Oral, Children's Allergy Medicine Oral, Children's Allergy Relief (diphenhyd) Oral, Children's Antihistamine Oral, Children's Complete Allergy Oral, Children's Wal-Dryl Allergy Oral, Child's Benadryl Allergy Oral, Complete Allergy Medication Oral, Complete Allergy Medicine Oral, Complete Allergy Oral, Complete Allergy Relief Oral, Compoz Oral, Cough Control (diphenhydramine) Oral, Diahist Oral, Dibenil Oral, DIPH-AL ALLERGY Oral, Diphedryl Allergy Oral, Diphedryl Allergy Relief Oral, Diphedryl Child Oral, Diphedryl Clear Oral, Diphen AF Oral, Diphenadryl Oral, Diphen-Allergy Oral, Diphendryl Oral, Diphenedryl Oral, Diphenhist Oral, Diphenyl Oral, Diphenylin Oral, Dormarex 2 Oral, DPH-Elixir Oral, Dytuss Oral, Easy Sleep Oral, EZ Nite Sleep Oral, Fenylhist Oral, Forty Winks Oral, Genahist Oral, Gen-D-Phen Oral, Geri-Dryl Oral, Harbermine Oral, Healamine Oral, Hydramine Oral, Hydramyn Oral, Komadryl Oral, Kosher Care Allergy Relief Oral, Lodryl Oral, Medi-Diphen Oral, Medi-Sleep Max Strength Oral, Naramin Oral, Nervine Oral, Nidryl Oral, Nightime Sleep Oral, Nighttime Allergy Relief Oral, NightTime Sleep Aid (diphenhydramine) Oral, Night-Time Sleep Oral, Nilin Oral, Nitetime Sleep Aid Oral, Noradryl Oral, Nordryl Oral, Nu-Med Alledryl Oral, Nytol Oral, Nyt-Time Sleep Oral, Orestyl Oral, Ormir Oral, Pardryl Oral, Parlyn Oral, Pediacare Allergy Oral, Penta-Diphen Oral, Pharbedryl Oral, Pharm-A-Dry Oral, Phen-Amine-25 Oral, Phen-Amine-50 Oral, Phendry Oral, Polydryl Allergy Oral, Polydryl Cough Oral, Polydryl Oral, ProHist Oral, Q-Dryl Oral, Quenalin Oral, Rest Simply Nighttime Sleep Oral, Restfully Sleep Oral, Robalyn Oral, Sandryl Oral, Scot-Tussin Allergy Relief Oral, Siladryl DAS Oral, Siladryl Oral, Siladryl SA Oral, Silphen Cough Oral, Simply Allergy Oral, Simply Sleep Oral, Sleep Aid (diphenhydramine) Oral, Sleep Aid Liquid Gels Max St Oral, Sleep Aid Max Strength (diphenhydramine) Oral, Sleep Formula Oral, Sleep II Oral, Sleep Oral, Sleep Safe Oral, Sleep Serene Oral, Sleep Tablet (diphenhydramine) Oral, Sleep Tabs Oral, Sleep Time Oral, Sleep-Ettes D Oral, Sleep-Ex Oral, Sleep-Eze 3 Oral, Sleepgels Oral, Sleepinal Maximum Strength Oral, Sleepinal Oral, Sleeping Oral, Sleeptabs Oral, Sleep-Tabs Oral, Sominex Formula 2 Oral, Sominex Maximum Strength Oral, Sominex Oral, Somnicaps Oral, Somnitab Oral, Somnitabs Formula Ii Oral, Theraflu Multi Symptom Oral, Total Allergy Medicine Oral, Tranquil Oral, Triaminic Allergy Oral, Triaminic Cough/Runny Nose Oral, Trux-Adryl Oral, Tusstat Oral, Twilite Oral, Ultra Sleep (diphenhydramine HCl) Oral, Uni-Bent Oral, Uni-Bentle Oral, Unisom (diphenhydramine) Oral, Unisom Sleepgels Oral, Unisom SleepMelts Oral, Valdrene Oral, Valu-Dryl Allergy Oral, Valu-Dryl Child's Allergy Oral, Valu-Dryl Oral, Vicks QlearQuil Nighttime Allergy Relief Oral, Wal-dryl Allergy Oral, Wal-Sleep Z Oral, Wal-Som (diphenhydramine) Oral, Z-Sleep Oral, ZzzQuil Oral

All generic drug interactions for diphenhydramine oral (lists will include brand and generic names):
Monitor CloselyPotential for interaction

chlorpheniramine-pseudoeph-dextromethorph-acetaminophen oral and diphenhydramine oral

chlorpheniramine-pseudoeph-dextromethorph-acetaminophen oral and diphenhydramine oral both increase sedation and drowsiness.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyUse Caution/Monitor.

chlorpheniramine-pseudoeph-dextromethorph-acetaminophen oral and diphenhydramine oral

chlorpheniramine-pseudoeph-dextromethorph-acetaminophen oral and diphenhydramine oral both increase sedation.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Never use this combination of drugs because of high risk for dangerous interaction


Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed


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Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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