
crizotinib oral brand names and other generic formulations include:
pimozide oral brand names and other generic formulations include:
crizotinib oral and pimozide oral
crizotinib oral and pimozide oral both increase causing a dangerous abnormal heart rhythm. Pimozide should not be taken with drugs that may increase the risk of abnormal heart beats (prolong the QT interval) and should be avoided.
crizotinib oral and pimozide oral
crizotinib oral and pimozide oral both increase QTc interval. Pimozide is contraindicated with drugs that may prolong the QT interval. Coadministration of crizotinib with CYP3A substrates with narrow therapeutic indices should be avoided.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant