
cyclosporine modified oral brand names and other generic formulations include:
Gengraf Oral, Neoral Oral, SangCya Oral
pravastatin oral brand names and other generic formulations include:
cyclosporine modified oral and pravastatin oral
cyclosporine modified oral increases toxicity of pravastatin oral by Other mechanism. Combination increases risk of muscle damage.
cyclosporine modified oral and pravastatin oral
cyclosporine modified oral increases toxicity of pravastatin oral by Other (see comment). Cyclosporine, an OATP1B1 inhibitor, with pravastatin, OATP1B1 substrate, may increase risk of myopathy. Initiate pravastatin dose at 10 mg/day and not to exceed 20 mg/day in patients who are also receiving cyclosporine.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant