Drug interactions with cyclosporine opht and everolimus oral

cyclosporine opht brand names and other generic formulations include:

Restasis Opht

All generic drug interactions for cyclosporine opht (lists will include brand and generic names):

everolimus oral brand names and other generic formulations include:

Afinitor Disperz Oral, Afinitor Oral, Zortress Oral

All generic drug interactions for everolimus oral (lists will include brand and generic names):
Monitor CloselyPotential for significant interaction (monitoring by your doctor is likely required)

cyclosporine opht and everolimus oral

cyclosporine opht will increase the level or effect of everolimus oral by altering drug metabolism.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyModify Therapy/Monitor Closely.

cyclosporine opht and everolimus oral

cyclosporine opht will increase the level or effect of everolimus oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Everolimus is a CYP3A4 and P-gp substrate. Prescribing information for coadministration with cyclosporine (a CYP3A4 and P-gp strong inhibitor) depends on everolimus indication and brand. Avoid coadministration if used for renal cell carcinoma (Afinitor). If used for kidney transplant immunosuppression (Zortress), reduce cyclosporine dose and use target serum concentration to reduce nephrotoxicity.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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