
cyclosporine opht brand names and other generic formulations include:
ivacaftor oral brand names and other generic formulations include:
cyclosporine opht and ivacaftor oral
cyclosporine opht will increase the level or effect of ivacaftor oral by altering drug metabolism. May increase drug blood levels.
cyclosporine opht and ivacaftor oral
cyclosporine opht will increase the level or effect of ivacaftor oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Reduce ivacaftor dose if coadministered with moderate CYP3A4 inhibitors. See specific ivacaftor-containing product for precise dosage modification.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant