
dabrafenib oral brand names and other generic formulations include:
Tafinlar Oral
apremilast oral brand names and other generic formulations include:
Otezla Oral, Otezla Starter Oral
dabrafenib oral and apremilast oral
dabrafenib oral will decrease the level or effect of apremilast oral by altering drug metabolism. Effect of apremilast may be reduced.
dabrafenib oral and apremilast oral
dabrafenib oral will decrease the level or effect of apremilast oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Coadministration with strong CYP inducers results in a significant decrease of systemic exposure of apremilast, which may result in loss of efficacy
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant