
dabrafenib oral brand names and other generic formulations include:
Tafinlar Oral
elvitegravir oral brand names and other generic formulations include:
Vitekta Oral
dabrafenib oral and elvitegravir oral
dabrafenib oral will decrease the level or effect of elvitegravir oral by altering drug metabolism. Avoid this combination. Blood levels of elvitegravir may be reduced decreasing effectiveness.
dabrafenib oral and elvitegravir oral
dabrafenib oral will decrease the level or effect of elvitegravir oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid; coadministration with CYP3A inducers may result in decreased plasma concentrations of elvitegravir and/or a concomitantly administered protease inhibitor and lead to loss of therapeutic effect and to possible resistance
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant