
dabrafenib oral brand names and other generic formulations include:
Tafinlar Oral
ivabradine oral brand names and other generic formulations include:
Corlanor Oral
dabrafenib oral and ivabradine oral
dabrafenib oral will decrease the level or effect of ivabradine oral by altering drug metabolism. Combination increases blood levels of ivabradine and should be avoided.
dabrafenib oral and ivabradine oral
dabrafenib oral will decrease the level or effect of ivabradine oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid coadministration of ivabradine with moderate CYP3A4 inducers.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant