Drug interactions with dabrafenib oral and netupitant-palonosetron oral

dabrafenib oral brand names and other generic formulations include:

Tafinlar Oral

All generic drug interactions for dabrafenib oral (lists will include brand and generic names):

netupitant-palonosetron oral brand names and other generic formulations include:

Akynzeo Oral

All generic drug interactions for netupitant-palonosetron oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

dabrafenib oral and netupitant-palonosetron oral

dabrafenib oral will decrease the level or effect of netupitant-palonosetron oral by altering drug metabolism. Blood levels or effect of netupitant may be decreased.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Serious - Use AlternativeAvoid or Use Alternate Drug.

dabrafenib oral and netupitant-palonosetron oral

dabrafenib oral will decrease the level or effect of netupitant-palonosetron oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Netupitant is mainly metabolized by CYP3A4; avoid use in patients who are chronically using a strong CYP3A4 inducer

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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