
dabrafenib oral brand names and other generic formulations include:
Tafinlar Oral
rolapitant oral brand names and other generic formulations include:
Varubi Oral
dabrafenib oral and rolapitant oral
dabrafenib oral will decrease the level or effect of rolapitant oral by altering drug metabolism. This combination reduces blood levels and effect of rolapitant.
dabrafenib oral and rolapitant oral
dabrafenib oral will decrease the level or effect of rolapitant oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Long-term coadministration of strong CYP3A4 inducers with rolapitant may significantly decrease rolapitant efficacy.
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant