Drug interactions with dabrafenib oral and warfarin oral

dabrafenib oral brand names and other generic formulations include:

Tafinlar Oral

All generic drug interactions for dabrafenib oral (lists will include brand and generic names):

warfarin oral brand names and other generic formulations include:

Athrombin-K Oral, Coufarin Oral, Coumadin Oral, Jantoven Oral, Panwarfin Oral, Sofarin Oral

All generic drug interactions for warfarin oral (lists will include brand and generic names):
Monitor CloselySignificant interaction possible (monitoring by your doctor required)

dabrafenib oral and warfarin oral

dabrafenib oral will decrease the level or effect of warfarin oral by Other mechanism.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyUse Caution/Monitor.

dabrafenib oral and warfarin oral

dabrafenib oral will decrease the level or effect of warfarin oral by Other (see comment). Warfarin's less potent R-enantiomer is metabolized in part by CYP3A4 (and also CYP1A2 and CYP2C19). Monitor INR more frequently if coadministered with inducers of these isoenzymes and adjust warfarin dose if needed.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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