
dantrolene iv brand names and other generic formulations include:
Dantrium IV, Revonto IV, Ryanodex IV
nicardipine oral brand names and other generic formulations include:
Cardene Oral, Cardene SR Oral
dantrolene iv and nicardipine oral
dantrolene iv , nicardipine oral . Either increases toxicity of the other by Mechanism: additive drug effects. Combination may increase risk of heart failure and high blood potassium levels.
dantrolene iv and nicardipine oral
dantrolene iv , nicardipine oral . Either increases toxicity of the other by Mechanism: pharmacodynamic synergism. Rare incidence of cardiovascular collapse and marked hyperkalemia observed when coadministered; may be higher risk with nondihydropyridine calcium channel blockers
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant