Drug interactions with diclofenac oral and pirfenidone oral

diclofenac oral brand names and other generic formulations include:

Voltaren Oral, Voltaren-XR Oral

All generic drug interactions for diclofenac oral (lists will include brand and generic names):

pirfenidone oral brand names and other generic formulations include:

Esbriet Oral

All generic drug interactions for pirfenidone oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

diclofenac oral and pirfenidone oral

diclofenac oral will increase the level or effect of pirfenidone oral by altering drug metabolism. Blood levels of pirfenidone may be increased. Avoid taking this combination if possible, if not, your doctor may decrease your dose.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Serious - Use AlternativeAvoid or Use Alternate Drug.

diclofenac oral and pirfenidone oral

diclofenac oral will increase the level or effect of pirfenidone oral by affecting hepatic enzyme CYP1A2 metabolism. Avoid; coadministration of pirfenidone and moderate CYP1A2 inhibitors result in moderately increased exposure to pirfenidone; if unable to avoid, decrease dose of moderate CYP1A2 inhibitor

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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