Drug interactions with drospirenone-ethinyl estradiol oral and ombitasvir-paritaprevir-ritonavir-dasabuvir oral

drospirenone-ethinyl estradiol oral brand names and other generic formulations include:

Gianvi (28) Oral, Loryna (28) Oral, Nikki (28) Oral, Ocella Oral, Syeda Oral, Vestura (28) Oral, Yasmin (28) Oral, YAZ (28) Oral, Zarah Oral

All generic drug interactions for drospirenone-ethinyl estradiol oral (lists will include brand and generic names):

ombitasvir-paritaprevir-ritonavir-dasabuvir oral brand names and other generic formulations include:

Viekira Pak Oral

All generic drug interactions for ombitasvir-paritaprevir-ritonavir-dasabuvir oral (lists will include brand and generic names):
ContraindicatedNever use this combination of drugs because of high risk for dangerous interaction

drospirenone-ethinyl estradiol oral and ombitasvir-paritaprevir-ritonavir-dasabuvir oral

drospirenone-ethinyl estradiol oral , ombitasvir-paritaprevir-ritonavir-dasabuvir oral . Either increases toxicity of the other by unspecified interaction mechanism. This combination increases the risk of liver related side effects. Stop ethinyl estradiol-containing medications before starting ombitasvir/paritaprevir/ritonavir, and/or dasabuvir. Restart ethinyl estradiol containing medications 2 weeks after the hepatitis C drug treatment of completed.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
ContraindicatedContraindicated.

drospirenone-ethinyl estradiol oral and ombitasvir-paritaprevir-ritonavir-dasabuvir oral

drospirenone-ethinyl estradiol oral , ombitasvir-paritaprevir-ritonavir-dasabuvir oral . Either increases toxicity of the other by unspecified interaction mechanism. ALT elevations >5 x ULN (including some >20 x ULN) observed in clinical trials when ethinyl estradiol was coadministered with ombitasvir/paritaprevir/ritonavir, with or without dasabuvir. Discontinue ethinyl estradiol-containing medications before initiating ombitasvir/paritaprevir/ritonavir, and/or dasabuvir. Restart ethinyl estradiol containing medication ~2 weeks after hepatitis C combination drug regimen completed.

Clinical Drug Interactions Source: Medscape from WebMD
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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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