elvitegravir oral brand names and other generic formulations include:
Vitekta Oral
bosentan oral brand names and other generic formulations include:
elvitegravir oral and bosentan oral
elvitegravir oral , bosentan oral altering drug metabolism. Elvitegravir increases bosentan levels, and bosentan decreases elvitegravir levels; your doctor will manage the dosage and timing of each drug carefully.
elvitegravir oral and bosentan oral
elvitegravir oral , bosentan oral affecting hepatic/intestinal enzyme CYP3A4 metabolism. Elvitegravir increases bosentan levels, and bosentan decreases elvitegravir levels; if elvitegravir received for >10 days, start bosentan at 62.5 mg/day or every other day; if patient taking bosentan and starting elvitegravir, discontinue bosentan at least 36 hr beforehand, may resume bosentan at 62.5 mg/day or every other day after 10 days
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant