
elvitegravir oral brand names and other generic formulations include:
Vitekta Oral
rifabutin oral brand names and other generic formulations include:
elvitegravir oral and rifabutin oral
elvitegravir oral , rifabutin oral altering drug metabolism. Elvitegravir increases rifabutin levels, and rifabutin decreases elvitegravir levels. Your doctor may reduce dose of rifabutin; no dose adjustment of elvitegravir is required.
elvitegravir oral and rifabutin oral
elvitegravir oral , rifabutin oral affecting hepatic/intestinal enzyme CYP3A4 metabolism. Elvitegravir increases rifabutin levels, and rifabutin decreases elvitegravir levels; when rifabutin, a potent CYP3A inducer is used with elvitegravir (with a protease inhibitor and ritonavir), reduce dose of rifabutin by at least 75%; no dose adjustment of elvitegravir is required
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant