
esomeprazole magnesium oral brand names and other generic formulations include:
Nexium 24HR Oral, Nexium Oral, Nexium Packet Oral
aminophylline rect brand names and other generic formulations include:
Truphylline Rect
esomeprazole magnesium oral and aminophylline rect
esomeprazole magnesium oral increases toxicity of aminophylline rect by Other mechanism. Prolonged use of proton pump inhibitors can cause hypochlorhydria (little or no stomach acid). Combination may increase risk of adverse effects.
esomeprazole magnesium oral and aminophylline rect
esomeprazole magnesium oral increases toxicity of aminophylline rect by Other (see comment). Prolonged use of proton pump inhibitors can cause hypochlorhydria, which in turn causes peristalsis in small intestine to increase and peristalsis in the proximal colon to decrease; monitor for toxicity
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant