Drug interactions with esomeprazole magnesium oral and nelfinavir oral

esomeprazole magnesium oral brand names and other generic formulations include:

Nexium 24HR Oral, Nexium Oral, Nexium Packet Oral

All generic drug interactions for esomeprazole magnesium oral (lists will include brand and generic names):

nelfinavir oral brand names and other generic formulations include:

Viracept Oral

All generic drug interactions for nelfinavir oral (lists will include brand and generic names):
ContraindicatedNever use this combination of drugs because of high risk for dangerous interaction

esomeprazole magnesium oral and nelfinavir oral

esomeprazole magnesium oral decreases levels of nelfinavir oral by unspecified interaction mechanism. Combination reduces the effect of nelfinavir.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
ContraindicatedContraindicated.

esomeprazole magnesium oral and nelfinavir oral

esomeprazole magnesium oral decreases levels of nelfinavir oral by unspecified interaction mechanism. Coadministration may lead to loss of nelfinavir virologic response and development of resistance; mechanism may be CYP2C19 inhibition of nelfinavir conversion to active M8 metabolite, and also PPIs decreasing gastric pH resulting in decreased nelfinavir absorption

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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