
etravirine oral brand names and other generic formulations include:
dolutegravir oral brand names and other generic formulations include:
Tivicay Oral
etravirine oral and dolutegravir oral
etravirine oral will decrease the level or effect of dolutegravir oral by speeding up drug metabolism. Combination decreases blood levels of dolutegravir.
etravirine oral and dolutegravir oral
etravirine oral will decrease the level or effect of dolutegravir oral by increasing metabolism. Etravirine (a strong UGT1A/CYP3A inducer) significantly reduces dolutegravir plasma concentrations, but the effect of etravirine is mitigated by coadministration of lopinavir/ritonavir or darunavir/ritonavir, and is expected to be mitigated by atazanavir/ritonavir; do not use with etravirine without coadministration of atazanavir/ritonavir, darunavir/ritonavir, or lopinavir/ritonavir
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant