Drug interactions with etravirine oral and phenytoin oral

etravirine oral brand names and other generic formulations include:

Intelence Oral

All generic drug interactions for etravirine oral (lists will include brand and generic names):

phenytoin oral brand names and other generic formulations include:

Dilantin Infatabs Oral, Dilantin-125 Oral, Lorantoin Oral

All generic drug interactions for phenytoin oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

etravirine oral and phenytoin oral

etravirine oral will increase the level or effect of phenytoin oral by altering drug metabolism. Taking these drugs together may decrease the therapeutic effect of etravirine; In addition, etravirine may increase phenytoin concentrations.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Serious - Use AlternativeAvoid or Use Alternate Drug.

etravirine oral and phenytoin oral

etravirine oral will increase the level or effect of phenytoin oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Etravirine and phenytoin should not be coadministered. Concomitant use of etravirine and phenytoin may result in decreased etravirine plasma concentrations and loss of therapeutic effect of etravirine. In addition, etravirine may inhibit the CYP metabolism of phenytoin, resulting in increased phenytoin concentrations.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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