Drug interactions with famotidine oral and atazanavir-cobicistat oral

famotidine oral brand names and other generic formulations include:

Acid Controller Oral, Acid Reducer (famotidine) Oral, Heartburn Prevention Oral, Heartburn Relief (famotidine) Oral, Mylanta AR Oral, Pepcid AC Oral, Pepcid Oral, Pepcid RPD Oral

All generic drug interactions for famotidine oral (lists will include brand and generic names):

atazanavir-cobicistat oral brand names and other generic formulations include:

Evotaz Oral

All generic drug interactions for atazanavir-cobicistat oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

famotidine oral and atazanavir-cobicistat oral

famotidine oral will decrease the level or effect of atazanavir-cobicistat oral by reducing stomach acidity. This interaction may occur when both drugs are taken by mouth. H2-receptor antagonists (H2RA) reduce blood levels of atazanavir. Administer atazanavir 2 hr before or 1 hr after these medications. Take atazanavir simultaneously with the H2RA or at least 10 hours afterward.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Serious - Use AlternativeAvoid or Use Alternate Drug.

famotidine oral and atazanavir-cobicistat oral

famotidine oral will decrease the level or effect of atazanavir-cobicistat oral by increasing gastric pH. Applies only to oral form of both agents. Atazanavir solubility decreases as pH increases. Substantially reduced plasma concentrations of atazanavir are expected if H2-receptor antagonists (H2RA) are coadministered. For treatment-naïve patients, take atazanavir simultaneously with the H2RA or at least 10 h afterwards. See dosage adjustment recommendations if coadministered in treatment-experienced patients.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

Check for more interactions with the Drug Interaction Checker

Check Now »

Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

Health Solutions From Our Sponsors