
glycerol phenylbutyrate oral brand names and other generic formulations include:
Ravicti Oral
tacrolimus oral brand names and other generic formulations include:
Astagraf XL Oral, Envarsus XR Oral, Hecoria Oral, Prograf Oral
glycerol phenylbutyrate oral and tacrolimus oral
glycerol phenylbutyrate oral will decrease the level or effect of tacrolimus oral by altering drug metabolism. Glycerol phenylbutyrate may reduce blood levels and effect of certain drugs.
glycerol phenylbutyrate oral and tacrolimus oral
glycerol phenylbutyrate oral will decrease the level or effect of tacrolimus oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Glycerol phenylbutyrate is a weak inducer of CYP3A4. Monitor for decreased efficacy of CYP3A4 substrates that have a narrow therapeutic index.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant