
ibuprofen-diphenhydramine citrate oral brand names and other generic formulations include:
Advil PM Oral, Motrin PM Oral
tacrolimus oral brand names and other generic formulations include:
Astagraf XL Oral, Envarsus XR Oral, Hecoria Oral, Prograf Oral
ibuprofen-diphenhydramine citrate oral and tacrolimus oral
ibuprofen-diphenhydramine citrate oral , tacrolimus oral . Either increases toxicity of the other by Other mechanism. Taking this combination increases risk of nephrotoxicity (kidney problems).
ibuprofen-diphenhydramine citrate oral and tacrolimus oral
ibuprofen-diphenhydramine citrate oral , tacrolimus oral . Either increases toxicity of the other by Other (see comment). Concomitant administration increases risk of nephrotoxicity
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant