Drug interactions with ibuprofen-oxycodone oral and metoprolol tartrate-hydrochlorothiazide oral

ibuprofen-oxycodone oral brand names and other generic formulations include:

Combunox Oral

All generic drug interactions for ibuprofen-oxycodone oral (lists will include brand and generic names):

metoprolol tartrate-hydrochlorothiazide oral brand names and other generic formulations include:

Lopressor HCT Oral

All generic drug interactions for metoprolol tartrate-hydrochlorothiazide oral (lists will include brand and generic names):
Monitor CloselySignificant interaction possible (monitoring by your doctor required)

ibuprofen-oxycodone oral and metoprolol tartrate-hydrochlorothiazide oral

ibuprofen-oxycodone oral decreases effects of metoprolol tartrate-hydrochlorothiazide oral by opposing drug effects. Associated with long term NSAID use (longer than 1 week). Blood pressure reducing effects may be reduced.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyUse Caution/Monitor.

ibuprofen-oxycodone oral and metoprolol tartrate-hydrochlorothiazide oral

ibuprofen-oxycodone oral decreases effects of metoprolol tartrate-hydrochlorothiazide oral by pharmacodynamic antagonism. Long term (>1 wk) NSAID use. NSAIDs decrease prostaglandin synthesis.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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