Drug interactions with ibuprofen-oxycodone oral and valsartan-hydrochlorothiazide oral

ibuprofen-oxycodone oral brand names and other generic formulations include:

Combunox Oral

All generic drug interactions for ibuprofen-oxycodone oral (lists will include brand and generic names):

valsartan-hydrochlorothiazide oral brand names and other generic formulations include:

Diovan HCT Oral

All generic drug interactions for valsartan-hydrochlorothiazide oral (lists will include brand and generic names):
Monitor CloselyPotential for significant interaction (monitoring by your doctor is likely required)

ibuprofen-oxycodone oral and valsartan-hydrochlorothiazide oral

ibuprofen-oxycodone oral decreases effects of valsartan-hydrochlorothiazide oral by opposing drug effects. Combination may reduce blood pressure reducing effect.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyModify Therapy/Monitor Closely.

ibuprofen-oxycodone oral and valsartan-hydrochlorothiazide oral

ibuprofen-oxycodone oral decreases effects of valsartan-hydrochlorothiazide oral by pharmacodynamic antagonism. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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