Drug interactions with itraconazole oral and aliskiren-amlodipine-hydrochlorothiazide oral

itraconazole oral brand names and other generic formulations include:

Onmel Oral, Sporanox Oral, Sporanox Pulsepak Oral

All generic drug interactions for itraconazole oral (lists will include brand and generic names):

aliskiren-amlodipine-hydrochlorothiazide oral brand names and other generic formulations include:

Amturnide Oral

All generic drug interactions for aliskiren-amlodipine-hydrochlorothiazide oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

itraconazole oral and aliskiren-amlodipine-hydrochlorothiazide oral

itraconazole oral will increase the level or effect of aliskiren-amlodipine-hydrochlorothiazide oral by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Should not be taken together.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Serious - Use AlternativeAvoid or Use Alternate Drug.

itraconazole oral and aliskiren-amlodipine-hydrochlorothiazide oral

itraconazole oral will increase the level or effect of aliskiren-amlodipine-hydrochlorothiazide oral by P-glycoprotein (MDR1) efflux transporter. Consider an alternative with no or minimal potential to inhibit CYP3A4. If concomitant use of strong CYP3A4 inhibitors is unavoidable, closely monitor for respiratory depression and sedation, and consider decreasing alfentanil dose necessary.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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