
itraconazole oral brand names and other generic formulations include:
Onmel Oral, Sporanox Oral, Sporanox Pulsepak Oral
amlodipine-valsartan-hydrochlorothiazide oral brand names and other generic formulations include:
itraconazole oral and amlodipine-valsartan-hydrochlorothiazide oral
itraconazole oral will increase the level or effect of amlodipine-valsartan-hydrochlorothiazide oral by Other mechanism.
itraconazole oral and amlodipine-valsartan-hydrochlorothiazide oral
itraconazole oral will increase the level or effect of amlodipine-valsartan-hydrochlorothiazide oral by Other (see comment). CCBs elicit negative inotropic effects which may be additive to those of itraconazole; additionally, itraconazole can inhibit the metabolism of calcium channel blockers. Monitor for adverse reactions. Concomitant drug dose reduction may be necessary.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant