Drug interactions with itraconazole oral and dabigatran etexilate oral

itraconazole oral brand names and other generic formulations include:

Onmel Oral, Sporanox Oral, Sporanox Pulsepak Oral

All generic drug interactions for itraconazole oral (lists will include brand and generic names):

dabigatran etexilate oral brand names and other generic formulations include:

Pradaxa Oral

All generic drug interactions for dabigatran etexilate oral (lists will include brand and generic names):
Monitor CloselyPotential for significant interaction (monitoring by your doctor is likely required)

itraconazole oral and dabigatran etexilate oral

itraconazole oral will increase the level or effect of dabigatran etexilate oral by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Whether taking dabigatran for Atrial Fibrillation or Deep Vein Thrombosis/Pulmonary Embolism (DVT/PE) your doctor will determine if you should take this combination of drugs based upon your creatinine clearance.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyModify Therapy/Monitor Closely.

itraconazole oral and dabigatran etexilate oral

itraconazole oral will increase the level or effect of dabigatran etexilate oral by P-glycoprotein (MDR1) efflux transporter. Atrial fibrillation: Avoid coadministering dabigatran with P-gp inhibitors if CrCl <30 mL/min. DVT/PE treatment: Avoid coadministering dabigatran with P-gp inhibitors if CrCl <50 mL/min

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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