
itraconazole oral brand names and other generic formulations include:
Onmel Oral, Sporanox Oral, Sporanox Pulsepak Oral
digoxin inj brand names and other generic formulations include:
Lanoxin Inj, Lanoxin Pediatric Inj
itraconazole oral and digoxin inj
itraconazole oral will increase the level or effect of digoxin inj by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter).
itraconazole oral and digoxin inj
itraconazole oral will increase the level or effect of digoxin inj by P-glycoprotein (MDR1) efflux transporter. Measure digoxin levels before initiating concomitant drugs. Monitor and consider reducing the digoxin dose by ~30-50% or modifying the dosing frequency.
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant