itraconazole oral brand names and other generic formulations include:
Onmel Oral, Sporanox Oral, Sporanox Pulsepak Oral
docetaxel iv brand names and other generic formulations include:
Docefrez IV, Taxotere IV
itraconazole oral and docetaxel iv
itraconazole oral will increase the level or effect of docetaxel iv by altering drug metabolism.
itraconazole oral and docetaxel iv
itraconazole oral will increase the level or effect of docetaxel iv by affecting hepatic/intestinal enzyme CYP3A4 metabolism. If coadministration is unavoidable, consider a 50% docetaxel dose reduction and monitor for increased docetaxel toxicities.
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant