itraconazole oral brand names and other generic formulations include:
Onmel Oral, Sporanox Oral, Sporanox Pulsepak Oral
ifosfamide iv brand names and other generic formulations include:
itraconazole oral and ifosfamide iv
itraconazole oral will decrease the level or effect of ifosfamide iv by altering drug metabolism.
itraconazole oral and ifosfamide iv
itraconazole oral will decrease the level or effect of ifosfamide iv by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Coadministration of CYP3A4 inhibitors may decrease the metabolism of ifosfamide to its active alkylating metabolites and decrease the efficacy of ifosfamide.
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant