
itraconazole oral brand names and other generic formulations include:
Onmel Oral, Sporanox Oral, Sporanox Pulsepak Oral
lansoprazole oral brand names and other generic formulations include:
Heartburn Relief 24 Hour Oral, Heartburn Treatment 24 Hour Oral, Prevacid 24Hr Oral, Prevacid Oral, Prevacid SoluTab Oral
itraconazole oral and lansoprazole oral
itraconazole oral will increase the level or effect of lansoprazole oral by altering drug metabolism.
itraconazole oral and lansoprazole oral
itraconazole oral will increase the level or effect of lansoprazole oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Separate proton pump inhibitors at least 2 hr before or 2 hr after itraconazole. Use of Sporanox oral solution (instead of the capsule) or administration of itraconazole with an acidic beverage (eg, cola) may minimize the significance of this interaction. Closely monitor for reduced itraconazole efficacy if combined.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant