
itraconazole oral brand names and other generic formulations include:
Onmel Oral, Sporanox Oral, Sporanox Pulsepak Oral
nintedanib oral brand names and other generic formulations include:
Ofev Oral
itraconazole oral and nintedanib oral
itraconazole oral increases levels of nintedanib oral by affects how the drug is eliminated from the body (via what is known as the P-glycoprotein [MDR1] transporter). Combination may increase risk of side effects.
itraconazole oral and nintedanib oral
itraconazole oral increases levels of nintedanib oral by P-glycoprotein (MDR1) efflux transporter. If nintedanib adverse effects occur, management may require interruption, dose reduction, or discontinuation of therapy
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant