
itraconazole oral brand names and other generic formulations include:
Onmel Oral, Sporanox Oral, Sporanox Pulsepak Oral
perindopril-amlodipine oral brand names and other generic formulations include:
Prestalia Oral
itraconazole oral and perindopril-amlodipine oral
itraconazole oral will increase the level or effect of perindopril-amlodipine oral by Other mechanism.
itraconazole oral and perindopril-amlodipine oral
itraconazole oral will increase the level or effect of perindopril-amlodipine oral by Other (see comment). CCBs elicit negative inotropic effects which may be additive to those of itraconazole; additionally, itraconazole can inhibit the metabolism of calcium channel blockers. Monitor for adverse reactions. Concomitant drug dose reduction may be necessary.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant