itraconazole oral brand names and other generic formulations include:
Onmel Oral, Sporanox Oral, Sporanox Pulsepak Oral
rilpivirine oral brand names and other generic formulations include:
itraconazole oral and rilpivirine oral
itraconazole oral increases levels of rilpivirine oral by altering drug metabolism. Monitor for fungal infections.
itraconazole oral and rilpivirine oral
itraconazole oral increases levels of rilpivirine oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. No rilpivirine dose adjustment is required. Clinically monitor for breakthrough fungal infections when azole antifungals are co-administered with rilpivirine.
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant