Drug interactions with itraconazole oral and rivaroxaban oral

itraconazole oral brand names and other generic formulations include:

Onmel Oral, Sporanox Oral, Sporanox Pulsepak Oral

All generic drug interactions for itraconazole oral (lists will include brand and generic names):

rivaroxaban oral brand names and other generic formulations include:

Xarelto Oral

All generic drug interactions for rivaroxaban oral (lists will include brand and generic names):
Monitor CloselySignificant interaction possible (monitoring by your doctor required)

itraconazole oral and rivaroxaban oral

itraconazole oral increases levels of rivaroxaban oral by altering drug metabolism. Combination may lead to significant increases in rivaroxaban blood levels and increase bleeding risk.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Monitor CloselyUse Caution/Monitor.

itraconazole oral and rivaroxaban oral

itraconazole oral increases levels of rivaroxaban oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid concomitant use of rivaroxaban and combined Pgp and strong CYP3A4 inhibitors. Combination may lead to significant increases in rivaroxaban levels and increase bleeding risk.

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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