
itraconazole oral brand names and other generic formulations include:
Onmel Oral, Sporanox Oral, Sporanox Pulsepak Oral
verapamil oral brand names and other generic formulations include:
Calan Oral, Calan SR Oral, Covera-HS Oral, Isoptin Oral, Isoptin SR Oral, Verelan Oral, Verelan PM Oral
itraconazole oral and verapamil oral
itraconazole oral will increase the level or effect of verapamil oral by altering drug metabolism. Dose adjustment may be required. Possible increase in side effects.
itraconazole oral and verapamil oral
itraconazole oral will increase the level or effect of verapamil oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Observe the patient for development of toxicity associated with verapamil (peripheral edema, dizziness, hypotension, flushing, headache). Consider reducing the dose of verapamil or withdrawing one of the agents.
Check for more interactions with the Drug Interaction Checker
Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant