Drug interactions with ketoconazole oral and regorafenib oral

ketoconazole oral brand names and other generic formulations include:

Nizoral Oral

All generic drug interactions for ketoconazole oral (lists will include brand and generic names):

regorafenib oral brand names and other generic formulations include:

Stivarga Oral

All generic drug interactions for regorafenib oral (lists will include brand and generic names):
Serious - Use AlternativePotential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

ketoconazole oral and regorafenib oral

ketoconazole oral will increase the level or effect of regorafenib oral by altering drug metabolism. Blood levels of regorafenib may be increased.

Patient Drug Interactions Source: RxList
© 2023 RxList, Inc.
Serious - Use AlternativeAvoid or Use Alternate Drug.

ketoconazole oral and regorafenib oral

ketoconazole oral will increase the level or effect of regorafenib oral by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Strong CYP3A4 inhibitors increase regorafenib levels and decrease exposure of the active metabolites M-2 and M-5

Clinical Drug Interactions Source: Medscape from WebMD
© 1994-2023 WebMD, LLC.

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Drug Interaction Categories

Contraindicated

Never use this combination of drugs because of high risk for dangerous interaction

Serious

Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed

Significant

Potential for significant interaction (monitoring by your doctor is likely required)

Minor

Interaction is unlikely, minor, or nonsignificant

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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