lansoprazole iv brand names and other generic formulations include:
dabrafenib oral brand names and other generic formulations include:
Tafinlar Oral
lansoprazole iv and dabrafenib oral
lansoprazole iv will decrease the level or effect of dabrafenib oral by reducing stomach acidity. This interaction may occur when both drugs are taken by mouth. Absorption of dabrafenib may be reduced by drugs that alter upper GI tract PH such as PPIs, H2-blockers and antacids.
lansoprazole iv and dabrafenib oral
lansoprazole iv will decrease the level or effect of dabrafenib oral by increasing gastric pH. Applies only to oral form of both agents. Drugs that alter upper GI tract pH (eg, PPIs, H2-blockers, antacids) may decrease dabrafenib solubility and reduce its bioavailability
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant