
lansoprazole iv brand names and other generic formulations include:
gefitinib oral brand names and other generic formulations include:
lansoprazole iv and gefitinib oral
lansoprazole iv decreases levels of gefitinib oral by reducing stomach acidity. This interaction may occur when both drugs are taken by mouth.
lansoprazole iv and gefitinib oral
lansoprazole iv decreases levels of gefitinib oral by increasing gastric pH. Applies only to oral form of both agents. Avoid coadministration of gefitinib with PPIs if possible. If treatment with a PPI is required, separate gefitinib and PPI doses by 12 hr.
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Drug Interaction Categories
Contraindicated
Never use this combination of drugs because of high risk for dangerous interaction
Serious
Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed
Significant
Potential for significant interaction (monitoring by your doctor is likely required)
Minor
Interaction is unlikely, minor, or nonsignificant